258 Study of mitochondrial respiratory chain on reconstructed human epidermis
نویسندگان
چکیده
منابع مشابه
Reconstructed Human Epidermis: an Efficient Prediction Tool
RHE has the ultimate advantage to grow donor epidermal cells in a serumfree culture environment: after rapidly proliferating preparative keratinocyte cultures have been obtained, the yielded epidermal cells are seeded on inert filter substrates that are lifted to the air-liquid interface in a humidified-air incubator. A fully-defined nutrient medium feeds the basal cells through the filter subs...
متن کاملMitochondrial respiratory-chain diseases.
s since January 1975, a full-text search capacity, and a personal archive for saving articles and search results of interest. All articles can be printed in a format that is virtually identical to that of the typeset pages. Beginning six months after publication the full text of all original articles and special articles is available free to nonsubscribers who have completed a brief registratio...
متن کاملThe mitochondrial respiratory chain.
In the present chapter, the structures and mechanisms of the major components of mammalian mitochondrial respiratory chains are reviewed. Particular emphasis is placed on the four protein complexes and their cofactors that catalyse the electron transfer pathway between oxidation of NADH and succinate and the reduction of oxygen to water. Current ideas are reviewed of how these electron transfer...
متن کاملBiochemical and molecular aspects of human mitochondrial respiratory chain disorders.
Functional mitochondrial respiratory chain and oxidative phosphorylation systems are obligate requirements for the normal function of most eukaryotic cells. When a defect of one of these systems occurs in humans, it results in a variety of clinical symptoms according to the severity of the defect and the tissues involved. Defects of all five multisubunit complcxes comprising the respiratory cha...
متن کاملThe Aerobic Mitochondrial Respiratory Chain
INTRODUCTION Fumarate reductase (FRD) catalyses the reduction of fumarate to succinate and is a key enzyme for the anaerobic functioning of many organisms respiring with fumarate as terminal electron acceptor. The ability to reduce fumarate is a common property among Gram-negative bacteria and some facultative anaerobic Gram-positive bacteria. The reduction of fumarate is also important in the ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.07.259